This database was created through the neurofeedback intervention of the SMOKEFREEBRAIN project (http://smokefreebrain.eu/). The Neurofeedback study aimed to investigating the role of combined training, including skin temperature training and alpha/theta neurofeedback training in smoking cessation. Training-induced effects in different psychological factors and possible neuroplastic alterations were explored. The study design included an initial clinical, behavioral, neurophysiological and neuropsychological evaluation that followed by five session of skin temperture training. Subsequently, another evaluation was performed following the procedures of the initial one. Then, twenty sessions of alpha/theta training were administered. After training completion another evaluation was performed. Three months after the end of intevention, participants underwent a follow-up evaluation following the same procedures as the baseline.